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Comparative studies

Finishing mortality in a swine production system using different PCV2 vaccination protocols

A comparison of mortality in finishing barns following the use of various PCV2 vaccination protocols was made in a specific swine production system in Quebec (Canada). Sows were vaccinated with Circovac (Merial) 7 and 4 weeks before farrowing and gilts twice before breeding. Piglets were vaccinated between 3 and 7 weeks after weaning and Ingelvac CircoFLEX® was compared with either no vaccination or a two dose vaccine in a total of 171,464 piglets. Of these 58,752 were born to sows which had received sow vaccine prior to farrowing and 112,712 to sows which had not. Sow vaccine did not appear to reduce piglet mortality of either vaccinated or unvaccinated piglets.

Both Ingelvac CircoFLEX® and the two dose piglet vaccine significantly improved mortality rates.

Mortality rate
Piglet Vaccine With sow vaccination Without sow vaccination
Piglet vaccination significantly lowered mortality rate
None 10.7% (n=18,101) 10.4% (n=80,799)
Two dose vaccine 3.8% (n=26,425) 3.9% (n=24,041)
Ingelvac CircoFLEX® 3.4% (n=14,226) 3.1% (n=7,872)

Cardinal F. Finishing mortality in a swine production system using different PCV2 vaccination protocols. IPVS 2008

(This paper is an update of that previously presented at the Allan D Leman Swine Conference.)

Comparative performance of barns of pigs

Ingelvac CircoFLEX® was evaluated along with other PCV2 vaccines in a total of 58,316 pigs over three months in a commercial production system which had been suffering acute PCV associated disease (PCVAD). Piglets were vaccinated at between 8 and 18 days old with either Ingelvac CircoFLEX®, an alternative single dose vaccine or a two dose vaccine. All three products reduced mortality. Ingelvac CircoFLEX® provided protection comparable to the two dose product but significantly better than the other single dose product (p<0.05).


  • Ingelvac CircoFLEX®: 398 out of 19,842, 2.0%
  • Two dose vaccine: 392 out of 22,321, 1.8%
  • Alternative single dose vaccine: 591 out of 16,153, 3.7%

Kolb J et al. Comparative performance of barns of pigs vaccinated with Ingelvac CircoFLEX® or other PCV2 vaccines. Ingelvac CircoFLEX® Symposium, September 15 2007, St. Paul, Minnesota

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